As an essentially child of the 60's I decided after my first couple of trips to LOS in the early 90's that a stay in Thailand was a current day stand-in for some of the "experimenting", if you know what I'm saying, that I used to enjoy back then. (Yes, I was a scientist in 1967... )
Put another way it was a sense of heightened experience where things seemed familiar but aspects were unexpected, exciting or disturbing: the food was meat/veg/rice but the unusual combinations of flavors & the incendiary chiles would often literally take my breath away.... the constant heat & humidity weighed down on me like a physical presence always, and the long breeze-free nights offered no respite (most of my early memories there are nighttime scenes colored by beer & rice whiskey)... grey & green tinged florescent light shadows echoing everywhere....unceasing lines of traffic pulsing down all the main roads at all hours day & night & I would turn into a minor soi & somebody would be leading an elephant towards me... walking into a disco (Angels, or Marine) & seeing a wall to wall mob of beautiful smiling girls in the smoke... meeting the local expats, some of whom could be described as eccentric, criminal?, murky backgrounds & misfits... and then the ladyboys.....
Granted after 16 years I have become acclimated & it's not a psychoactive event now. All those things I mentioned, and more, are taken in stride, more or less, & enjoyed thoroughly, routinely... And there is always something new to contemplate, which is an antidote to my day to day routine back home.